Timolol as a migraine acute attack therapy: randomized, OTCs control study
نویسندگان
چکیده
Background: Migraine is manifested by recurrent headache attacks, with variable characteristics and associated symptoms. Oral beta blockers are widely used to prevent reduce the frequency these attacks. However, use of topical for acute treatment still controversial. Aims: In this randomized double – armed study, we aim compare efficacy Timolol 0.5% eyedrops compared other over-the-counter (OTC) medications migraine. Methods: Fifty-seven patients were randomly allocated group A (treatment group: eyedrops), B (control OTC drugs including Non-steroidal anti-inflammatory (NSAIDs), caffeine, aspirin, acetaminophen). The primary outcome was pain reduction. Secondary measures included reducing nausea, vomiting, photophobia, phonophobia. Results: Median reduction higher than timolol (6, 4 prospectively) a significant U-test (p
منابع مشابه
Migraine--treatment of acute attack.
The treatment of an acute attack of classical or common migraine is sleep, an antinauseant such as metoclopramide, an analgesic, either aspirin or paracetamol, and in some patients 1 or 2 mg of ergotamine tartrate. Treatment should be given as early in the attack as possible and all drugs should, if possible, be given in a soluble or effervescent form. When vomiting occurs early in the attack, ...
متن کاملTwelve-week, randomized, multicenter study comparing a fixed combination of brimonidine-timolol with timolol as therapy adjunctive to latanoprost
OBJECTIVE To evaluate the additive intraocular pressure (IOP)-lowering efficacy and safety of fixed-combination brimonidine 0.2%/timolol 0.5% compared with timolol 0.5% at peak and trough effect when used as therapy adjunctive to latanoprost 0.005% in patients with glaucoma or ocular hypertension who require additional IOP lowering. METHODS In this prospective, randomized, multicenter, invest...
متن کاملTreating an acute attack of migraine.
STEP 2 Recognize Migraine as a Process.—While headache and migraine are often considered synonymous, they are not. Migraine is always more than headache. Learning the non-headache symptoms associated with your migraine is essential to early recognition of an attack. The headache-associated symptoms of a migraine attack are divided into 3 components: (1) symptoms occurring before the headache be...
متن کاملEfficacy of acupuncture for acute migraine attack: a multicenter single blinded, randomized controlled trial.
OBJECTIVE We aim to investigate the efficacy of acupuncture for acute migraine attacks comparing with sham acupuncture. DESIGN The study was designed as a multicenter, single-blinded, randomized controlled clinical trial. SETTING AND PATIENTS From March 2007 to February 2009, 150 patients were randomly allocated to verum or sham acupuncture group in a ratio of 1:1. INTERVENTIONS Every pat...
متن کاملKinetic Oscillation Stimulation as Treatment of Acute Migraine: A Randomized, Controlled Pilot Study
OBJECTIVE To assess the relief of migraine pain, especially in the acute phase, by comparing active treatment, ie, kinetic oscillation stimulation (KOS) in the nasal cavity, with placebo. BACKGROUND Exploratory trials testing the efficacy of KOS on migraine patients indicated that this treatment could be a fast-acting remedy for acute migraine pain. METHOD Thirty-six patients were randomize...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Mansoura Medical Journal
سال: 2023
ISSN: ['1110-211X', '2735-3990']
DOI: https://doi.org/10.58775/2735-3990.1370